When Jerry gets a cold he gets no help from Tom who chooses instead to use the mouse's down time to taunt the little guy and eat all of his favorite treats. Jerry resorts to help from Uncle Pecos who, after trying a few Texas remedies, mixes a home brewed Texas tonic to knock the cold p-p-p-plum out. As a side effect of the Tabasco fueled brew, the mouse is breathing fire within minutes. When Tom catches the same cold and gets a dose of the brew, it's an all-out flame war! Good thing Uncle Pecos is there to put the fire out!